Gene information
Official symbol PLAUR
Official full name plasminogen activator, urokinase receptor
Gene type protein-coding gene
Chromosome19q13
Alias symbolURKR; UPAR; CD87
Gene familyCD molecules; LY6/PLAUR domain containing
Resources
Entrez Gene 5329
HGNC HGNC:9053
Ensembl ENSG00000011422
Vega OTTHUMG00000182778
UCSC uc002oxf.3
GO terms: 67 records
GO Description Category LogP Number of genes Detail
GO:0001934 positive regulation of protein phosphorylation GO Biological Processes -52.8272623 84 More
GO:0005788 endoplasmic reticulum lumen GO Cellular Components -47.2996164 57 More
GO:0005925 focal adhesion GO Cellular Components -8.40302345 46 More
GO:0006935 chemotaxis GO Biological Processes -33.1726887 55 More
GO:0007596 blood coagulation GO Biological Processes -44.7281461 45 More
GO:0007599 hemostasis GO Biological Processes -44.1075001 45 More
GO:0009611 response to wounding GO Biological Processes -63.1714102 77 More
GO:0010466 negative regulation of peptidase activity GO Biological Processes -24.1438543 35 More
GO:0010638 positive regulation of organelle organization GO Biological Processes -6.49207636 47 More
GO:0010755 regulation of plasminogen activation GO Biological Processes -10.5063145 8 More
GO:0010821 regulation of mitochondrion organization GO Biological Processes -7.09757912 23 More
GO:0010822 positive regulation of mitochondrion organization GO Biological Processes -5.15923818 8 More
GO:0010951 negative regulation of endopeptidase activity GO Biological Processes -24.7873219 35 More
GO:0019898 extrinsic component of membrane GO Cellular Components -2.13392265 23 More
GO:0022407 regulation of cell-cell adhesion GO Biological Processes -32.4337382 53 More
GO:0022409 positive regulation of cell-cell adhesion GO Biological Processes -25.7751074 39 More
GO:0030055 cell-substrate junction GO Cellular Components -9.04790297 48 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030162 regulation of proteolysis GO Biological Processes -41.2267045 73 More
GO:0030193 regulation of blood coagulation GO Biological Processes -37.6853179 30 More
GO:0030667 secretory granule membrane GO Cellular Components -8.32957622 38 More
GO:0031225 anchored component of membrane GO Cellular Components -4.51589396 20 More
GO:0034110 regulation of homotypic cell-cell adhesion GO Biological Processes -6.42713539 7 More
GO:0034112 positive regulation of homotypic cell-cell adhesion GO Biological Processes -5.83914312 5 More
GO:0035579 specific granule membrane GO Cellular Components -4.58725293 14 More
GO:0042060 wound healing GO Biological Processes -56.2139708 65 More
GO:0042330 taxis GO Biological Processes -33.0828571 55 More
GO:0042581 specific granule GO Cellular Components -15.6202777 22 More
GO:0043086 negative regulation of catalytic activity GO Biological Processes -41.1437610 130 More
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -5.11653120 8 More
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -14.7594418 39 More
GO:0043388 positive regulation of DNA binding GO Biological Processes -12.0675836 19 More
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway GO Biological Processes -3.18614571 7 More
GO:0045785 positive regulation of cell adhesion GO Biological Processes -29.6368249 50 More
GO:0045861 negative regulation of proteolysis GO Biological Processes -27.9905009 43 More
GO:0050817 coagulation GO Biological Processes -44.4773041 45 More
GO:0050818 regulation of coagulation GO Biological Processes -40.0839917 32 More
GO:0050878 regulation of body fluid levels GO Biological Processes -57.9546976 69 More
GO:0051099 positive regulation of binding GO Biological Processes -11.1715489 31 More
GO:0051101 regulation of DNA binding GO Biological Processes -9.69427751 24 More
GO:0051346 negative regulation of hydrolase activity GO Biological Processes -26.0030636 42 More
GO:0051917 regulation of fibrinolysis GO Biological Processes -20.6622986 13 More
GO:0052547 regulation of peptidase activity GO Biological Processes -35.5643317 55 More
GO:0052548 regulation of endopeptidase activity GO Biological Processes -34.9486589 53 More
GO:0061041 regulation of wound healing GO Biological Processes -35.8633788 36 More
GO:0070613 regulation of protein processing GO Biological Processes -7.71267127 10 More
GO:0090199 regulation of release of cytochrome c from mitochondria GO Biological Processes -6.79373102 8 More
GO:0090200 positive regulation of release of cytochrome c from mitochondria GO Biological Processes -3.39931914 4 More
GO:0098636 protein complex involved in cell adhesion GO Cellular Components -5.90313372 12 More
GO:0098637 protein complex involved in cell-matrix adhesion GO Cellular Components -3.72261873 5 More
GO:1900046 regulation of hemostasis GO Biological Processes -39.0044157 31 More
GO:1901184 regulation of ERBB signaling pathway GO Biological Processes -3.96203474 12 More
GO:1901186 positive regulation of ERBB signaling pathway GO Biological Processes -3.03839152 7 More
GO:1902532 negative regulation of intracellular signal transduction GO Biological Processes -29.4927428 92 More
GO:1903034 regulation of response to wounding GO Biological Processes -34.9293555 38 More
GO:1903317 regulation of protein maturation GO Biological Processes -7.52692728 10 More
GO:1905286 serine-type peptidase complex GO Cellular Components -11.3739342 10 More
GO:1905368 peptidase complex GO Cellular Components -4.61293625 9 More
GO:1905369 endopeptidase complex GO Cellular Components -3.16416938 6 More
GO:1905370 serine-type endopeptidase complex GO Cellular Components -8.85311859 8 More
GO:2000116 regulation of cysteine-type endopeptidase activity GO Biological Processes -14.4496812 41 More
GO:2000117 negative regulation of cysteine-type endopeptidase activity GO Biological Processes -4.79670615 8 More
GO:2001233 regulation of apoptotic signaling pathway GO Biological Processes -35.8481080 51 More
GO:2001234 negative regulation of apoptotic signaling pathway GO Biological Processes -32.1748782 40 More
GO:2001242 regulation of intrinsic apoptotic signaling pathway GO Biological Processes -16.0885267 23 More
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway GO Biological Processes -12.4318822 16 More
GO:2001267 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway GO Biological Processes -4.22212529 4 More
KEGG pathways: 2 records
KEGG Description Category LogP Number of genes Detail
hsa04610 Complement and coagulation cascades KEGG Pathway -50.1154932 39 More
hsa05205 Proteoglycans in cancer KEGG Pathway -18.5545131 27 More
Drug-Gene interaction
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Related drugs: 3 records
Related studies: 12 records
Molecular factor Omics type Application Objective MI type Reference
urokinase plasminogen activator surface receptor proteomics medium predictor acute myocardial infarction[diagnosis] acute myocardial infarction Schernthaner C et al. Eur J Clin Invest. 2017
urokinase plasminogen activator surface receptor proteomics medium predictor acute ST elevation myocardial infarction[diagnosis] acute ST elevation myocardial infarction Schernthaner C et al. Eur J Clin Invest. 2017
urokinase plasminogen activator surface receptor proteomics medium predictor acute non-ST elevation myocardial infarction[diagnosis] acute non-ST elevation myocardial infarction Schernthaner C et al. Eur J Clin Invest. 2017
urokinase plasminogen activator surface receptor proteomics death[prognosis (bad)] ST elevation myocardial infarction Lyngbaek S et al. Am J Cardiol. 2012
urokinase plasminogen activator surface receptor proteomics recurrent myocardial infarction[prognosis (bad)] ST elevation myocardial infarction Lyngbaek S et al. Am J Cardiol. 2012
urokinase plasminogen activator surface receptor proteomics recurrent myocardial infarction[prognosis (bad)] ST elevation myocardial infarction Lyngbaek S et al. Am J Cardiol. 2012
urokinase plasminogen activator surface receptor proteomics myocardial infarction[diagnosis] myocardial infarction Rasmussen LJ et al. HIV Med. 2016
urokinase plasminogen activator surface receptor proteomics good predictor major adverse cardiovascular events[prognosis (bad)] acute myocardial infarction Wlazel RN et al. Arch Med Sci. 2019
urokinase plasminogen activator surface receptor proteomics medium predictor death[prognosis (bad)] acute myocardial infarction Sorensen NA et al. Clin Res Cardiol. 2019
urokinase plasminogen activator surface receptor proteomics death[prognosis (bad)] acute myocardial infarction Sorensen NA et al. Clin Res Cardiol. 2019
urokinase plasminogen activator surface receptor proteomics death[prognosis (bad)] acute myocardial infarction Sorensen NA et al. Clin Res Cardiol. 2019
urokinase plasminogen activator surface receptor proteomics non-cardiac death[prognosis (bad)] ST elevation myocardial infarction Sando A et al. Clin Biochem. 2020
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